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	Provedor de dados BJMBR (2) Autor da Silva,M.A. (2) Alves,R.C.B. (1) Dias da Silva,W. (1) Melo,A.R. (1) Moreno,C. (1) Nascimento,P.A. (1) Okazaki,K. (1) Oliveira,E.M. (1) Petricevich,V.L. (1) Suzuki,M.F. (1) Ueda,C. (1) Mais... Palavra-chave BCG (1) Bacillus Calmette-Guérin (1) Blood lymphocytes (1) Breast cancer (1) Comet assay (1) DNA damage (1) DNA repair (1) Ionizing radiation (1) Mycobacterium bovis (1) Tuberculosis (1) Vaccine (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2001 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última A single strain of Mycobacterium bovis bacillus Calmette-Guérin (BCG) grown in two different media evokes distinct humoral immune responses in mice BJMBR Petricevich,V.L.; Ueda,C.; Alves,R.C.B.; da Silva,M.A.; Moreno,C.; Melo,A.R.; Dias da Silva,W.. Two attenuated bacillus Calmette-Guérin (BCG) preparations derived from the same Moreau strain, Copenhagen but grown in Sauton medium containing starch and bacto-peptone (onco BCG, O-BCG), or asparagine (intradermal BCG, ID-BCG), exhibited indistinguishable DNA sequences and bacterial morphology. The number of viable bacilli recovered from spleen, liver and lungs was approximately the same in mice inoculated with the vaccines and was similarly reduced (over 90%) in mice previously immunized with either BCG vaccine. The humoral immune response evoked by the vaccines was, however, distinct. Spleen cell proliferation accompanying the growth of bacilli in tissue was significantly higher in mice inoculated with O-BCG. These cells proliferated in vitro upon... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacillus Calmette-Guérin; BCG; Tuberculosis; Mycobacterium bovis; Vaccine. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000100010 Evaluation of radioinduced damage and repair capacity in blood lymphocytes of breast cancer patients BJMBR Nascimento,P.A.; da Silva,M.A.; Oliveira,E.M.; Suzuki,M.F.; Okazaki,K.. Genetic damage caused by ionizing radiation and repair capacity of blood lymphocytes from 3 breast cancer patients and 3 healthy donors were investigated using the comet assay. The comets were analyzed by two parameters: comet tail length and visual classification. Blood samples from the donors were irradiated in vitro with a 60Co source at a dose rate of 0.722 Gy/min, with a dose range of 0.2 to 4.0 Gy and analyzed immediately after the procedure and 3 and 24 h later. The basal level of damage and the radioinduced damage were higher in lymphocytes from breast cancer patients than in lymphocytes from healthy donors. The radioinduced damage showed that the two groups had a similar response when analyzed immediately after the irradiations. Therefore, while... Tipo: Info:eu-repo/semantics/article Palavras-chave: Comet assay; DNA damage; DNA repair; Ionizing radiation; Breast cancer; Blood lymphocytes. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200003 Registros recuperados: 2 Primeira ... 1 ... Última

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